What’s the molecules telling?

65 year old male presented with non healing ulcer over the pinna of right ear for 5 months. A biopsy from the lesion was done and following is the report. Carcinoma with basaloid features and pigmentation – biopsy right pinna. Immuno staining: P63 – diffuse strong positivity. P40 – diffuse moderate positivity. BerEP4 – negative.

Temporal bone cancer staging systems

Staging of cancers is essential for patient counselling, treatment planning, predict treatment outcome and survival. Most commonly followed staging system for head and neck malignancies is the Tumor, Node, Metastasis (TNM staging system) by the American Joint Committee on Cancer (AJCC). Because of the relative rarity of temporal bone cancers, a universally accepted temporal bone […]

NICE guidelines for Cochlear implantation in children and adults

According to the definition by American Academy of Family Physicians, Clinical practice guidelines are statements that include recommendations intended to optimize patient care. The National Institute for Health and Care Excellence (NICE) is a non-departmental public body in England, that provides national guidance and advice to improve health and social care. On 7th March 2019, […]

Its all in the genes!

A 42 year old female was seen at an outside facility for progressive bilateral hearing loss and was referred to the otology clinic. On further enquiry, she gave history of chronic head ache, mild balance difficulties and past history of tonic-clonic seizures, treated with anti-epileptics for a year. Physical examination revealed an alert and oriented […]

World Hearing Day

Globally it is estimated that over 5% of the world’s population i.e around 466 million people – have disabling hearing loss (432 million adults and 34 million children). Unaddressed hearing loss is the leading cause of morbidity and poses an annual cost of $750 billion globally. It is estimated that by 2050 over 900 million […]

WHO launches “hearWHO” app for mobile devices to help detect hearing loss

To mark the World Hearing Day, the World Health Organization (WHO) has launched “hearWHO“, a free application for smart mobile devices which allows people to check their hearing regularly and intervene early in case of hearing loss. Over 5% of the world’s population i.e around 466 million people – have disabling hearing loss (432 million […]

Recurrent Meningitis with Hearing loss

A 12 year old male child was referred from pediatric department following resolution of third episode of meningitis, with complaints of left side hearing loss since childhood. Parents noticed the hearing loss on left side when the child was in fourth standard. No newborn hearing screening was done for the child at birth. Investigations Blood / […]

I can’t hear you!

A 45-year-old locomotive driver consulted his family physician because of ringing sensation in both his ears for the past 5 years.  Away from work, he had difficulty understanding conversations in crowded rooms, and he said he often argued with his wife about the volume of the television set. He also complaints of depression that began soon […]

Painful swelling of ear in a middle aged man

35-year-old man presented to the ear, nose and throat outpatient department with a 1 week history of painful swelling of the right ear. He was having recurrent episodes of similar illness in both ears, for the past 5 years, for which he was treated multiple times with antibiotics and analgesics. These episodes used to subside […]

Noise Induced Hearing loss (NIHL)

Noise induced hearing loss (NIHL) is defined as reduction in auditory acuity (hearing ability) associated with long term exposure to loud sounds. It is the second most common form of sensorineural hearing deficit, after presbycusis (age-related hearing loss). An early term for the condition was “boilermakers’ disease,” because so many workers who made steam boilers developed hearing […]